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DiabeGen System: preventive strategies and use of genetic tests

The Eurospital DiabeGen Step I° and II° kits represent effective clinical tools for identification of at risk patients, mostly children and teenagers, before the onset of the disease.

This could help to plan in the best way their clinical follow-up. In accordance to this idea, a recent paper states that Type 1 Diabetes genetic screening might prevent children/teenagers from useless sufferance, as only 4% of enrolled subjects, and therefore with a known HLA, suffered from the usual diabetic ketoacidosis versus 15-20% of children from the general population.

This aspect underlines how an early preventive diagnosis might prevent from hospitalization due to ketoacidosis and save, at least partially, the ß cells of the patients.


  • DiabeGen  I° Step - 12 test - code 9192
  • DiabeGen II° Step - 12 test - code 9193




DiabeGen - I° and II° step for the assessment of risk and/or protection to the onset of Type 1 Diabetes Mellitus

The DiabeGen system allows to identify the degree of risk or the protection to Diabetes Mellitus Type I.

DiabeGen - I° step allows to detect the alleles predisposing to Type 1 Diabetes Mellitus (DQA1*05/DQB1*02-DR3; DQA1*03/DQB1*03:02-DR4) and allows to detect the protective allele DQB1*06:02 and the homozygosis or heterozygosis status of DRB1*04.

In case that is not present the protective allele and there is a degree of risk given by DRB1 * 04, the use of DiabeGen II ° step allows typed in high resolution (4 digits) allele DRB1 * 04 and then determine degree risk or protection.




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